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Clinton Stewart Selected Research

Neoplasms (Cancer)

1/2021Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma.
1/2019CNS Penetration of Cyclophosphamide and Metabolites in Mice Bearing Group 3 Medulloblastoma and Non-Tumor Bearing Mice.
5/2012Phase I study of vincristine, irinotecan, and ¹³¹I-metaiodobenzylguanidine for patients with relapsed or refractory neuroblastoma: a new approaches to neuroblastoma therapy trial.
1/2011Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma.
9/2010A phase II trial and pharmacokinetic study of oxaliplatin in children with refractory solid tumors: a Children's Oncology Group study.
1/2010A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: clinical outcomes, pharmacokinetics and molecular correlation.
10/2009Initial testing (stage 1) of lapatinib by the pediatric preclinical testing program.
5/2009Expression of the multi-drug resistance proteins and the pregnane X receptor in treated and untreated retinoblastoma.
11/2006Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study.
10/2005Topotecan combination chemotherapy in two new rodent models of retinoblastoma.
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Clinton Stewart Research Topics

Disease

12Neoplasms (Cancer)
01/2021 - 01/2002
4Retinoblastoma (Glioblastoma, Retinal)
06/2011 - 10/2005
3Medulloblastoma
01/2021 - 11/2006
3Brain Neoplasms (Brain Tumor)
01/2019 - 11/2006
3Thrombocytopenia (Thrombopenia)
11/2006 - 01/2005
2Glioma (Gliomas)
01/2021 - 01/2005
2Breast Neoplasms (Breast Cancer)
10/2009 - 05/2009
2Neutropenia
11/2006 - 01/2005
1Hemorrhage
01/2019
1Meningitis
04/2013
1Arachnoiditis
04/2013
1Neuroblastoma
05/2012
1Glioblastoma (Glioblastoma Multiforme)
01/2010
1Typical Teratoid Rhabdoid Tumor
11/2006
1Leukopenia
11/2006
1Vomiting
11/2006
1Primitive Neuroectodermal Tumors (PNET)
11/2006
1Rhabdoid Tumor (Rhabdoid Tumors)
11/2006
1Diarrhea
01/2005
1Disease Progression
01/2005
1Colonic Neoplasms (Colon Cancer)
08/2002
1Carcinoma (Carcinomatosis)
08/2002

Drug/Important Bio-Agent (IBA)

6Topotecan (Hycamtin)FDA LinkGeneric
04/2013 - 01/2002
3Carboplatin (JM8)FDA LinkGeneric
01/2011 - 01/2002
2Vincristine (Oncovin)FDA LinkGeneric
05/2012 - 10/2005
2Irinotecan (Camptosar)FDA LinkGeneric
05/2012 - 01/2005
2Oxaliplatin (Eloxatin)FDA LinkGeneric
09/2010 - 11/2006
2Lapatinib (GW572016)FDA Link
01/2010 - 10/2009
1lorlatinibIBA
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1Phosphotransferases (Kinase)IBA
01/2021
1carboxyethylphosphoramide mustardIBA
01/2019
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2019
1SolutionsIBA
01/2019
1Adrenal Cortex Hormones (Corticosteroids)IBA
04/2013
1RadiopharmaceuticalsIBA
05/2012
13-Iodobenzylguanidine (Iobenguane)IBA
05/2012
1Proto-Oncogene Proteins c-mdm2IBA
06/2011
1nutlin 3IBA
06/2011
19 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA
01/2011
1Pharmaceutical PreparationsIBA
09/2010
1epidermal growth factor receptor VIIIIBA
01/2010
1EnzymesIBA
01/2010
1Tyrosine Kinase InhibitorsIBA
10/2009
1Proteins (Proteins, Gene)FDA Link
05/2009
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
05/2009
1Pregnane X ReceptorIBA
05/2009
1XenobioticsIBA
05/2009
1Alanine Transaminase (SGPT)IBA
11/2006
1Platinum Compounds (Compounds, Platinum)IBA
11/2006
1Retinaldehyde (Retinal)IBA
10/2005
1LuciferasesIBA
10/2005
1Green Fluorescent ProteinsIBA
10/2005
1Drug CombinationsIBA
10/2005
1Etoposide (VP 16)FDA LinkGeneric
10/2005
1Temozolomide (Temodar)FDA LinkGeneric
01/2005
1Capecitabine (Xeloda)FDA Link
01/2005
15- (3- methyl- 1- triazeno)imidazole- 4- carboxamide (MTIC)IBA
01/2005
1Fluorouracil (Carac)FDA LinkGeneric
08/2002
1Leucovorin (Folinic Acid)FDA Link
08/2002
1Death Domain ReceptorsIBA
08/2002
1RNA (Ribonucleic Acid)IBA
08/2002
1Antineoplastic Agents (Antineoplastics)IBA
01/2002
1trioctyl phosphine oxide (TOPO)IBA
01/2002

Therapy/Procedure

7Drug Therapy (Chemotherapy)
01/2021 - 01/2002
5Therapeutics
04/2013 - 01/2002
2Combination Drug Therapy (Combination Chemotherapy)
10/2005 - 01/2005
1Cryotherapy (Therapy, Cold)
10/2005
1Laser Therapy (Surgery, Laser)
10/2005
1Radiotherapy
01/2005